Glossary

A
Arteriovenous: Relating to or affecting both an artery and a vein.
Ataxia: A lack of muscle coordination which may affect speech, eye movements, swallowing, walking, picking up objects, and other voluntary movements.
Autoimmune disease: An illness where the body’s immune system attacks its own tissues. The immune system typically “seeks and destroys” harmful invaders, but in autoimmune diseases, it targets the body itself. Patients may have unusual antibodies circulating in their blood that attack their own tissues.

B
Bacterial: Caused by bacteria. Bacteria are single-celled microorganisms that can live independently or within a host organism. Unlike viruses, they reproduce on their own.
Bladder: The organ that collects urine from the kidneys before it is excreted. It is a hollow, muscular, elastic organ located on the pelvic floor, and urine enters through the ureter and exits via the urethra.
Bowel: The section of the digestive system between the stomach and the anus, consisting of the small and large intestines.

C
Cerebrospinal fluid: A watery fluid that is continuously produced and absorbed, circulating in the brain's ventricles and around the brain and spinal cord. (Abbreviated CSF)
Corticosteroids: Steroid hormones produced by the adrenal glands or synthetically created. These are used to reduce swelling and immune responses and treat various conditions.
Cyclophosphamide: A drug used to treat cancer, also acting as an immunosuppressant to decrease the body’s immune response. It is used for severe autoimmune diseases and transverse myelitis.

D
Demyelinating: Refers to the damage of the myelin sheath of neurons, impairing nerve signal conduction and leading to loss of sensation, movement, cognition, or other functions, depending on the affected nerves.

E
EEG: Electroencephalogram – a test that measures electrical activity in the brain using sensors attached to the scalp.
Encephalitis: A rare condition that causes inflammation of the brain, typically due to infections.

F
Farnsworth-Munsell hue test: A test to assess color vision by separating individuals into classes of superior, average, or low color discrimination and identifying areas of color confusion in color-deficient individuals.

I
Immunodulation: The process of influencing the immune system, either to enhance or suppress its activity, often using drugs.
Immunoglobulin: Antibodies produced by the immune system in response to bacteria, viruses, or other foreign substances.
Inflammation: The immune system’s response to harmful stimuli, marked by pain, redness, heat, swelling, and loss of function.
Ischemia: The restriction or blockage of blood flow in a blood vessel, which can cause heart attacks, strokes, and visual field losses.
Ishihara color chart: A test using colored plates to diagnose color vision deficiencies, ranging from difficulty distinguishing colors to complete color blindness.

L
Lupus erythematosus: A group of autoimmune diseases in which the immune system attacks normal, healthy tissues, affecting various organs like joints, skin, kidneys, blood cells, heart, and lungs.

M
Magnetic resonance imaging (MRI): A test that uses a magnetic field and radio wave pulses to create images of the body’s internal structures. MRI is used to detect abnormalities that other imaging methods may miss, including those in the brain and spinal cord.
Methotrexate: A medication used to treat arthritis and autoimmune conditions, blocking certain enzymes in the immune system.
Microglial cells: Immune cells in the central nervous system that act as the first line of defense.
Multiple sclerosis: An autoimmune disease affecting the brain and spinal cord, characterized by demyelination and resulting in neurological symptoms.
Muscle spasticity: A condition where muscles become stiff, restricting movement.
Myelin: The protective layer around nerves that allows for efficient signal transmission. Damage to myelin slows down nerve impulses.

N
Neuropathy: A condition involving damage to peripheral nerves, leading to symptoms like numbness, tingling, pain, and muscle weakness.

O
Optic Nerve: Also known as cranial nerve II, it transmits visual information from the retina to the brain.

P
Paresthesias: Abnormal sensations such as tingling, numbness, or burning, often felt in the hands, feet, arms, or legs.
Paraparesis: Partial paralysis and weakness of the lower limbs.
Plasma exchange (Plasmapheresis): A treatment for autoimmune diseases that involves removing blood, separating cells from plasma, and returning the cells to the body with fresh plasma.

S
Sarcoidosis: A chronic disease causing immune cells to form clusters, typically affecting the lungs, spleen, liver, and other organs.
Sjogren’s syndrome: A chronic autoimmune disease where the immune system attacks moisture-producing glands, causing dry eyes, mouth, and sometimes other organs.
Spinal Cord: A vital part of the central nervous system extending from the brain down the back, surrounded by cerebrospinal fluid and protected by the vertebrae. It controls motor and sensory functions, including movement and autonomic functions.

T
T Cell: A type of white blood cell that attacks virus-infected cells and regulates the immune response.

V
Vasculitis: Inflammation of blood vessels caused by the immune system attacking blood vessels.
Viral: Caused by viruses, microorganisms that need living cells to replicate.